NONE 20260130064721574 wseas/wseas content-registration-form+ja@crossref.org content-registration-form International Journal of Applied Sciences & Development 2945-0454 Sami Makolli Higher Education Institute, UBT Prishtina, Lagjja Kalabria, 10 000 Prishtina, KOSOVO Terkida Prifti Department of Industrial Chemistry, Faculty of Natural Sciences, University of Tirana, ALBANIA Ilirjan Malollari Department of Industrial Chemistry, Faculty of Natural Sciences, University of Tirana, ALBANIA Pharmaceutical residues in hospital wastewater pose a significant environmental threat, particularly in developing regions like Albania where advanced treatment is lacking. This study investigates the kinetics of photocatalytic oxidation for degrading a mixture of ciprofloxacin, paracetamol, and ibuprofen in real hospital effluent using a pilot-scale reactor (50 L) installed in Vlora, Albania. The system employed suspended TiO₂ under UV-A irradiation. Kinetic analysis revealed that the degradation followed pseudo-first-order kinetics, with high correlation coefficients (R² > 0.95). The Langmuir-Hinshelwood model better described the process at higher concentrations. Under optimal conditions (1.5 g/L catalyst), removal efficiencies reached 92% for paracetamol, 85% for ciprofloxacin, and 78% for ibuprofen, with significant total organic carbon (TOC) reduction (60-70%). This study demonstrates that photocatalytic oxidation is a viable and effective tertiary treatment for pharmaceutical-laden wastewater in Albanian hospitals, providing a kinetic foundation for future scaling and implementation. 01 30 2026 01 30 2026 16 2 https://creativecommons.org/licenses/by/4.0/deed.en_US 10.37394/232029.2026.5.2 https://wseas.com/journals/asd/2026/a04asd-002(2026).pdf Akbari, M. Z., Xu, Y., Liang, C., & et al. (2024). 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