38c40382-9b46-4c59-8369-20391a5ddcf720250805132414796wseas:wseasmdt@crossref.orgMDT DepositWSEAS TRANSACTIONS ON BIOLOGY AND BIOMEDICINE2224-29021109-951810.37394/23208http://wseas.org/wseas/cms.action?id=40111720251720252210.37394/23208.2025.22https://wseas.com/journals/bab/2025.phpAndrew K.MartusevichLobachevsky University, Nizhny Novgorod, 603005, RUSSIAVladimir V.NazarovLobachevsky University, Nizhny Novgorod, 603005, RUSSIASergey V.PetrovLobachevsky University, Nizhny Novgorod, 603005, RUSSIATatiana B.KondratyevaSechenov University, Moscow, 119048, RUSSIATatiana V.KhlevchukSechenov University, Moscow, 119048, RUSSIAVera S.BadyanovaLobachevsky University, Nizhny Novgorod, 603005, RUSSIASergey P.PeretyaginAssociation of Russian Ozone Therapy, Nizhny Novgorod, 603109, RUSSIAThe purpose of this study was to analyze the possibility of detecting and evaluating the characteristics of fibrosis of palmar aponeurosis tissues in Dupuytren's disease using near-field resonant microwave sensing. The study involved 12 patients who underwent an examination before undergoing surgical treatment. The dielectric characteristics of the skin and underlying tissues were evaluated at 4 points, one of which was obviously in an unchanged area, and the rest in a potentially fibrous area. Near-field microwave sensing was performed using a proprietary hardware and software complex that included applicators with a radiation penetration depth of 2 to 5 mm. It has been established that in the area of fibroly transformed palmar aponeurosis, the actual part of the dielectric constant decreases significantly, and this process occurs fairly evenly at various points of the pathological focus. Our studies have also shown that the depth of fibrosis in the examined patients with Dupuytren's disease is approximately 3.5 mm.85202585202541541938https://wseas.com/journals/bab/2025/a765108-030(2025).pdf10.37394/23208.2025.22.38https://wseas.com/journals/bab/2025/a765108-030(2025).pdf10.1097/01.bth.0000186794.90431.a4I.T. Au-Yong, C.J. Wildin, J.J. Dias, R.E. Page, A review of common practice in Dupuytren surgery, Tech. Hand Up Extrem. Surg., vol. 9, iss. 4, 2005, pp. 178-187, doi: 10.1097/01.bth.0000186794.90431.a4. T.N. Yashina, A.V. Afanasyev, Surgical treatment of finger and hand contractures in Dupuytren's disease and its relapses, Modern technologies of diagnosis, treatment and rehabilitation of injuries and diseases of the upper limb, Moscow, 2007, pp. 266-267. I.Zh. Osmonaliev, G.I. Mikusev, R.F. 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