Ivan Todorin, Nicola Yanev, Metodi Traykov, Borislav Yurukov, "An Off-Lattice HP Model with Side-Chains and S-S Bridges Impact for Protein Folding Problem," WSEAS Transactions on Biology and Biomedicine, vol. 15, pp. 16-23, 2018, DOI:
Ivan Todorin, Nicola Yanev, Metodi Traykov, Borislav Yurukov. An Off-Lattice HP Model with Side-Chains and S-S Bridges Impact for Protein Folding Problem.
WSEAS Transactions on Biology and Biomedicine. 2018;15:16-23.
WSEAS Transactions on Biology and Biomedicine
Print ISSN: 1109-9518, E-ISSN: 2224-2902
Volume 15, 2018
An Off-Lattice HP Model with Side-Chains and S-S Bridges Impact for Protein Folding Problem
Authors: , , ,
Abstract: The proposed model takes into account highest degree of complexity – different size of radiuses of side-chains, mentioned below as radicals, and two stages of algorithm, including random structure initially and subsequent purposeful folding process according to the physical forces and energies. The objective function is three-componential – one member corresponding to the impact of the hydrophobic contacts of side-chains, next one to the impact of hydrogen bonds between peptide chain parts and third to the impact of S-S bridges.
Keywords:
Protein folding prediction, Bioinformatics, Drug Design, Willpower folding, HP model, Amino acid descriptors, S-S bridges
Pages: 16-23 WSEAS Transactions on Biology and Biomedicine, ISSN / E-ISSN: 1109-9518 / 2224-2902, Volume 15, 2018, Art. #3 DOI: *As the DOI is a unique identifier, it is already available in the pdf version.
**The DOI link will be activated in the first midst of January 2026.
×
Citation Tools